25  Jun 18

TRUFER -XT TABLET


DR SANJAY AGRAWAL
LEADING PHARMACEUTICAL CONSULTANT AND EDITOR-IN CHIEF OF IJMTODAY

- Ferrous Ascorbate - 100 mg
- Folic acid -1.5 mg
- Zinc Sulphate – 22.5 mg

DESCRIPTION

Addition of ascorbic acid converts the ferric form to ferrous form thus making it absorbable from duodenum and upper jejunum, resulting in considerable enhancement of the absorption of iron. It has been demonstrated that Fe(II) ascorbate is less easily oxidized than Fe(II) in ferrous sulphate. Absorption of ferrous ascorbate averaged 52% higher than ferrous sulphate in subjects. Thus when administered as ferrous ascorbate, Fe (II) salt is more resistant to oxidation at alkaline pH, delivers maximum amount of ferrous iron to the duodenal brush border and at the same time produces minimum GI adverse effects.

Folic Acid is essential for the metabolic processes of the body. Folic acid is necessary for the synthesis of nucleic acids and the formation of heme, the pigmented, iron-carrying component of the hemoglobin in red blood cells. A deficient intake of folic acid can impair the maturation of young red blood cells, resulting in folic-acid-deficiency anemia. Folic acid is essential for efficient Neural tube development during pregnancy which forms the brain and spinal cord. Pregnant women with an insufficient intake of folic acid are more likely to give birth prematurely or to deliver babies with low birth weight or with neural tube defects.

Zinc plays an important role in the development of Embryo and Fetus. It also prevents Pre-term births. Zinc aids in greater Infant Birth weights and Head circumferences

INDICATIONS

- Anemia (megaloblastic, nutritional)
- Premenstrual syndrome
- Iron deficiency syndrome
- Anemia’s of pregnancy

DOSAGE AND ADMINISTRATION

1-2 tablets daily, or as directed by the physician /dietician.

CONTRAINDICATIONS

Hypersensitivity, Hemochromatosis, Peptic ulcer, Hemosiderosis

PRECAUTIONS

Oral iron preparations may aggravate existing peptic ulcer, regional enteritis and ulcerative colitis. Iron compounds taken orally can impair the absorption of tetracycline antibiotics. Antacids given concomitantly with iron compounds decrease iron absorption.

ADVERSE EFFECTS

Constipation; darkened or green stools; diarrhea; loss of appetite; nausea; stomach cramps, pain, or upset; vomiting.

PREGNANCY & LACTATON

This combination improves fetal growth and develops immune system. Ferrous ascorbate in this combination has high bioavailability with least GI side effects. Folic acid is vital for cell division and growth. Zinc is essential for many functions, including growth and neurobehavorial development, immune and sensory functions.

PRESENTATION

TRUEFER-XT Tablet is available in blister of 1X10’s tablets.

  Dr. Kajal

10 Jul 2018
Very informative knowledge

  Dr. Pankaj

27 Jun 2018
Evergreen formulation in anemia.

  Dr. Payal

26 Jun 2018
Interesting

  Dr Reena

25 Jun 2018
Information is good.


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