The amount of daily vitamin B₁₂ recommended is primarily based on the age, although studies have shown that a person’s lifestyle such as vegans and also vegetarians, tobacco users, and obesity are at a higher risk of developing a B₁₂ deficiency in present day.

Cyanocobalamin is the form of B₁₂ most used in supplements because it is the cheapest, however, Methylcobalamin is rapidly gaining popularity. Research has shown that vitamin B₁₂ taken by mouth or as a muscular B₁₂ injection is equally effective at restoring B₁₂ levels in people with a deficiency.

A vitamin B₁₂ is an important water soluble vitamin and its deficiency can increase the risk of neurological issues and adverse side effects. It will lead to B ₁₂ deficit anemia. People who are anemic might experience soreness in the mouth or tongue, weight loss, diarrhea, and much more. An insufficient level of vitamin B₁₂ can become too low to meet the demands of the body. Therefore, if left untreated may progress to many irreversible neurological issues

There are many differences present between Methylcobalamin and cyanocobalamin, both of them have beneficial effects on health and can prevent B₁₂ deficiencies. One of the study found that treating seven B₁₂-deficient people with oral Methylcobalamin had normal vitamin B₁₂ levels in their blood in just 2 month. Few of the studies showed that Methylcobalamin was effective in reducing symptoms of diabetic neuropathy, a complication of diabetes that leads to nerve damage (15 Trusted Source). Also that, several animal studies has found that each form could have neuroprotective effects and may be beneficial in treating conditions that affect your nervous system. Filling nutritional gaps in our diet in Methylcobalamin a vitamin B₁₂ supplement helps in a wide rage.Cyanocobalamin is a synthetic form of vitamin B₁₂ that can be converted to the natural forms Methylcobalamin and adenosylcobalamin. When coming to Methylcobalamin the retention rate of this form is very high and is very useful in case of nutritional deficiencies.