Vitamin D3 (Cholecalciferol) 60000 I.U.
1 gm sachet in a box containing 20 such sachets
|Composition:||Each sachet contains 60,000 IU of Vitamin D3 (Cholecalciferol)|
Vitamin D is a fat-soluble vitamin. Vitamin D promotes calcium absorption in the small intestine and maintains adequate serum calcium and phosphate concentrations to enable normal mineralization of bone and to prevent hypocalcemic tetany. It is also needed for bone growth and bone remodeling by osteoblasts and osteoclasts.
Vitamin D is important for normal bone development and maintenance. Severe vitamin D deficiency causes rickets in children and osteomalacia in adults. Without sufficient vitamin D, bones can become thin, brittle, or misshapen. Vitamin D sufficiency prevents rickets in children and osteomalacia in adults. Together with calcium, vitamin D also helps prevent osteoporosis in elderly.
Vitamin D also plays an important role in modulation of cell growth, neuromuscular and immune function, and reduction of inflammation. Many genes encoding proteins that regulate cell proliferation, differentiation, and apoptosis are modulated in part by vitamin D.
It is currently agreed that the measurement of total serum 25-hydroxyvitamin D concentration (1 ng/mL corresponding to 2.5 nmol/L) is the best indicator to evaluate
The current cut offs proposed by the Institute of Medicine (IOM) are as follows:
Aspivit-D3 Sachet is indicated for prevention and treatment of vitamin D deficiency in adults.
Vitamin D deficiency can be result of dietary inadequacy, impaired absorption and use, increased requirement, or increased excretion. Vitamin D deficiency can occur when usual dietary intake is lower than recommended levels over time, exposure to sunlight is limited, the kidneys cannot convert 25(OH)D to its active form, or absorption of vitamin D from the digestive tract is inadequate.
Rickets and osteomalacia are the classical vitamin D deficiency diseases. In children, vitamin D deficiency causes rickets, a disease characterized by a failure of bone tissue to properly mineralize, resulting in soft bones and skeletal deformities.
In adults, vitamin D deficiency can lead to osteomalacia, resulting in weak bones. Symptoms of bone pain and muscle weakness can indicate inadequate vitamin D levels.
Current evidence also suggests beneficial actions of vitamin D supplementation in patients with diabetes, cardiovascular disorders and cognitive impairment.
Aspivit D3 sachet is recommended for prevention and treatment of vitamin D deficiency
Dissolve the contents of one sachet in a glass of milk or fruit juice and consume
|Adverse drug reactions:||
The recommended upper intake levels of vitamin D in different age groups are as follows:
Studies suggest that regular daily intake of up to 1,000 IU of vitamin D is free from any serious side effects.
A serum 25(OH) D concentration consistently >500 nmol/L (>200 ng/mL) is considered to be potentially toxic.
Vitamin D toxicity can cause non-specific symptoms such as anorexia, weight loss, polyuria, and cardiac arrhythmias. More seriously, it can also raise blood levels of calcium which leads to nausea, vomiting, constipation and in severe cases vascular and tissue calcification, with subsequent damage to the heart, blood vessels, and kidneys.
Regular intake of Vitamin D supplements have the potential to interact with several types of medications. A few examples are provided below.
Sachet : Cholecalciferol 60000 I.U.
1 Tablet or 1 Sachet once a day
|How to use:||
|Contraindications and Precautions:||
• As these ingredients are natural components of our body there seems to be no contra-indications except in patients who have known hypersensitivity to ingredient.