Brief Product Information on ASMETH-NP
Brief Product Information on ASMETH-NP

Dr. Sanjay Agrawal

Leading Pharmaceutical consultant and editor-in chief of IJMToday


ASMETH-NP is a combination of 3 medicines, i.e. Methylcobalamin, Nortriptyline and Pregabalin. Pregabalin is an alpha-2-delta ligand, which decreases pain by modulating calcium channel activity of the nerve cell. Nortriptyline is a tricyclic antidepressant which increases the level of chemical messengers (serotonin and nor-adrenaline) that stops the movement of pain signals in the brain cells. Methylcobalamin is a form of Vitamin D which helps in the production of Myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves). Methylcobalamin is useful in the treatment of nerve pain (neuropathic pain) This medicine calms the damaged or overactive nerves by acting on the brain. Thereby decreasing the pain sensation. It also helps in the degeneration of damaged nerves in the body.


  • Back pain
  • Diabetic neuropathy
  • Sciatica


1 Tablet daily after meal (preferable after lunch)


If the patient in suffering from the following diseases he should take doctor’s advice

  • Iron deficiency (Anemia)
  • Kidney diseases
  • Heart disease
  • Schizophrenia
  • Thyroid problems
  • Coronary Artery diseases
  • Calcium Deficiency
  • Potassium Deficiency
  • Bipolar disorders
  • Depression
  • Glaucoma
  • Angioedema


  • Constipation
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increase hearth rate
  • Dizziness
  • Sleepiness
  • Tiredness
  • Blurred vision
  • Dryness of mouth
  • Difficulty in urination
  • Uncoordinated body movements


Tablet should be taken after meal, refrain from alcohol during the course of the medicine.


Avoid using this medicine during pregnancy and lactation. Patients with kidney, liver or heart complications should use only with doctors advise.


10 tablets in a strip with box


  • This combination is very useful in sciatica patients, whereas the other drugs are ineffective.
  • This combination is effective in patients with low back pain.
  • This product is neuro protective.

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