COMPOSITION: Each capsule of Itcangus contains 200 mg of itraconazole.
DESCRIPTION: Itraconazole is an antifungal agent that belongs to the class of imidazoles. It works by inhibiting the cell wall synthesis in fungi. Itraconazole inhibits the activity of the enzyme cytochrome P-450-14α-demethylase, which is involved in the conversion of lanosterol to ergosterol. When the synthesis of ergosterol is inhibited, it leads to increased cellular permeability, leakage of the cellular components, and eventually leads to cell death. Other mechanisms by which itraconazole inhibits the fungal growth include inhibition of endogenous respiration, purine uptake inhibition, and impaired phospholipid biosynthesis.
INDICATIONS:
- Chromomycosis
- Esophageal candidiasis
- Histoplasposis
- Volvo vaginal candidiasis
- Para coccidioido
- Pomonary cocodiasis
- Sporotrichosis
- Aspergillosis
- Blastomycosis
- Dermatoses
- Coccidioidal meningitis
DOSES AND ADMINISTRATION: 1 capsule in a day after lunch or else as directed by the doctor or physician.
CONTRAINDICATIONS: In patients with congestive heart failure, onychomycosis, and those with liver and kidney impairment.
ADVERSE EFFECTS: Adverse effects of these medicines include hepatotoxicity, headache, constipation, nausea, fever, vomiting, dizziness, and upset stomach.
PRECAUTION: There are no sufficient and well-controlled studies when it comes to itraconazole administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss your condition with your doctor before taking this medicine.
PRESENTATION: It comes as 200 capsules, which are available in 10x1x4 strip packing.
WARNINGS: Patients who are suffering with liver and kidney impairment should consume under medical supervision.
USPs:
- Itcangus 200 cap is very safe.
- Less drug interaction.
- Can be given with or without food.
