Brief Product Information on ASMETH FORTE Tablet
Brief Product Information on ASMETH FORTE Tablet

Dr. Sanjay Agrawal

Leading Pharmaceutical consultant and editor-in chief of IJMToday


Asmeth Forte has a composition of Methylcobalamin 1.5 mg, Alpha Lipoic acid 100mg L-Methyl Folate 1.5 mg. Pyridoxal 5 Phosphate 3mg. It contains L-Methyl Folate a natural, active form of folic acid, methylcobalamin is a water-soluble form of Vitamin B12. Alpha lipoc acid helps lower blood sugar level. Its ability to inhibit free radicals may help people with diabetic peripheral neuropathy, who have pain, burning, itching, tingling, and numbness in arms and legs from nerve damage. And pyridoxal 5 phosphate an active form of Vitamin B6.

Methlycobalamin is a neurological active form of Vitamin B12 and occurs as a water-soluble vitamin in the body. It is a co-factor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anemia, it increases the erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Alpha lipoic acid, a Reactive Oxygen Species (ROS) has been involved in the induction and the progression of damage of many human disorders, such as heart infarction, cerebral ischemia, diabetic neuropathy, Alzheimer’s diseases etc. In several studies, alpha lipoic acid has been described potent anti-oxidant effect. This review highlights recent findings showing that alpha lipoic acid effectively reduces oxidative damage in brain and cardiac ischemia as well as in other pathological events related to reactive oxygen species increasing. Alpha lipoic acid is potent anti-oxidant and are present in broad variety of foods., are also available in several dietary supplements and their side effects are very rare. Therefore, alpha lipoc acid may play an important role in clinical preventive medicine and human nutrition.

L-Methyl folate unlike regular folic acid, does not require enzymatic conversion to L-Methyl folate in the body. By providing L-Methyl folate directly, this form of folic acid may have benefits for those who do not produce enough, L-Methyl folate in response to folic acid supplementation. For those who take proper doses of folic acid, Vitamin B12 and Vitamin B6 but is still suffer from higher than optimal homocysteine, L- Methyl folate may be the solution.

Pyridoxal 5 phosphate is used by many enzymes. It is readily absorbed by the intestine by the process which is preceded by dephosphorization to form pyridoxine. It helps metabolize homo cysteine to cysteine. Elevated serum levels of homo cystine (hyper homo cystemia) increase the risk of diabetic complications, such as peripheral neuropathy and the related complaints of numbness, tingling and burning sensation and non-healing port ulcers.



  • Hyperglycemia
  • Neuralgia
  • Atherosclerosis
  • Angina
  • Hyper Oxidation
  • Peripheral neuropathies


1 tablet daily after lunch or as directed by the dietician/physician


Asmeth Forte is contraindicated in cases of undiagnosed megaloblastic anemia, pernicious, a plastic or normo cystic anemia


Frequent resistance may occur in patients with depressed hematopoiesis, alcoholism, deficiency of other vitamins


Generally, Asmeth Forte is tolerated well. There might be minimal adverse events such as anorexia, nausea, vomiting and diarrhea.

Pregnancy and lactation: Asmeth Forte is recommended as folate is especially important for pregnant women. Healthy levels of the vitamin can even lower the risks of certain birth defects.


Asmeth forte is available in blister packing of 10×10 tablets.


Those patients who consume alcohol or have hematopoiesis should take the medicine under medical supervision


  • It’s a drug of choice for diabetic patients
  • Unique combination with full therapeutic concentration
  • Only single time administration

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