Dr. Sanjay Agrawal
Leading Pharmaceutical consultant and editor-in chief of IJMToday
COMPOSITION:
Each CEFIGEN-200 tablet contains Cefixime Trihydrate IP (equivalent to N-hydra cefixime) 200 mg.
DESCRIPTION:
Cefigen-200 is a brand name for the anti-biotic Cefixime, the 3rd generation cephalosporin anti-biotics. Cefigen-200 exhibits broad-spectrum activity, with a longer half-life and higher penetrability. Cefigen-200 treats major bacterial infections such as ear, nose and throat infections, upper respiratory tract infections and genito urinary tract infections.
Cefixime is one of the very few antibiotics that are stable against cephalosporinase and beta-lactamase activity. Cefixime is a beta- lactam antibiotic that works by inhibiting the cell wall synthesis in the bacterial cells. This drug binds to specific penicillin-binding protein (PBPs), which control the trans activation step of peptidoglycan synthesis. This binding between the PBPs and beta lactam ring of cefixime prevents the cell wall synthesis, eventually leading to the bacterial cell death.
INDICATIONS:
- Bronchitis
- Disseminated gonococcal infection
- Pelvic inflammatory diseases
- Prostatitis
- Community acquired Pneumonia
- Gonorrhea
- Lyme diseases
- Otitis media
- Pharyngitis
- Tonsilitis
- Typhoid fever
- Brucellosis
- Gonococcal urethritis
- Cervicitis
- Skin/ skin structure infections
- Otitis externa
- Urinary tract infections
- Bacterial sinusitis
DOSES AND ADMINISTRATION:
One tablet twice a day or as directed by the physician
CONTRAINDICATIONS
Cefigen-200 tablet is contraindicated in patients with hyper sensitivity towards Cefixime. This medicine is also contra indicated in patients with epilepsy, clostridium difficile infection, myasthenia gravis, renal insufficiency and seizures.
ADVERSE EFFECTS:
The adverse effects of this medicine include abdominal pain, nausea, vomiting, severe itching of the skin, insomnia, dizziness, emesis, dyspepsia, headache, diarrhea, eosinophilia, hallucination and sinus tachycardia.
PRECAUTIONS:
There are no sufficient and well controlled studies when it comes to Cefixime administration in pregnant women and nursing mothers, therefore if youare pregnant or nursing discuss with your doctor about your condition before taking this medicine.
WARNINGS:
Patients suffering from neurological complication should take this medicine under medical supervision
USPs:
- High successful rate
- Doses are convenient
- Less complications
PRESENTATION:
Cefigen-200 tablets are available in 10×10 alu-alu packing.
